A connection between senescence and stem cells caused by
a breast cancer-initiating protein
https://www.eurekalert.org/pub_releases/2021-05/cndi-acb051421.php
High levels of the protein RANK
triggers controlled cell death and aging which can delay the formation of
tumors in the early stages of cancer: “Located in the membrane of cells, when it binds to its partner RANKL, it
sends signals that stimulate the development of the mammary gland. When these
proteins do not work properly, breast cells begin to divide and multiply
uncontrollably, resulting in breast cancer.”
Mesenchymal Stem Cells Show Potential to Treat NTM Lung Infections
“Treatment with human mesenchymal stem
cells (MSCs) effectively lessened hard-to-treat non-tuberculous mycobacteria
(NTM) lung infection, and its associated weight loss, in a new mouse model
susceptible to these infections, an early study reported.”
AI tracks cell movements in stem cell colonies
https://www.scienceboard.net/index.aspx?sec=ser&sub=def&pag=dis&ItemID=2699
Using computer algorithms, scientists
were able to track individual cells as they grew in colonies and record their
movement precisely. “This technique gives us a much more comprehensive
view of how cells behave, how they work cooperatively, and how they come
together in physical space to form complex organs,” said co-author Todd
McDevitt.
Scientists identify small-molecule cocktail to improve stem cell
use in research and disease treatments
Stem cells are hypothetically able to
replicate forever, at least the pluripotent ones, and are intended to serve as
a source for specialized cells. But their growth is hampered by the stress of
growing in cell culture dishes and induced environments. However with use of a
new cocktail it can successfully diminish negative impacts of artificial
environments on cells intended to be used for medicinal purposes.
