Methylene Blue
Methylene blue, a compound used to treat a blood disorder
called methemoglobinemia, has a reputation for being a cognitive and
mitochondrial enhancer.
Methylene blue (MB), is a bioactive substance and a blue dye
developed by scientists in the 19th century for the textile industry.
Its use for upregulating mitochondria is the is the ultimate
performance-enhancing Biohack because your Mitochondria are the fundamental
energy generation mechanism that underlies everything else. It specifically
helps the respiration process in mitochondria to produce ATP, the energy
molecule that drives all physiological processes.
It was FDA approved for its treatment of methemoglobinemia
but has been used for decades for a variety of purposes and specific clinical
conditions like septic shock, infection and cardiac surgery.
Clinical and lab research has clearly proven the cognitive
benefits of methylene blue:
Rats that were treated with methylene blue showed
improvements in cognition and memory retention. This is also documented in
human studies in which short term memory was improved.
In a rat model of cerebral ischemia, MB was able to speed up
the removal of damaged mitochondria from a cell prior to cell death (mitophagy).
A clinical trial of twenty-six adults was conducted to
investigate whether low doses (0.5 – 4.0 mg/kg) of methylene blue (MB) could
increase brain activity and improve performance in memory tasks.
MB is also capable of reducing the mitochondrial damaging
effects of amyloid beta in animal models.
Methylene blue works by donating electrons to coenzyme Q and
possibly to cytochrome C, thus increasing cytochrome oxidase (complex IV)
activity and oxygen consumption thus improving the efficiency of the electron
transport chain in mitochondria to produce ATP
Methylene blue (MB) has been investigated in people with
Alzheimer’s dementia, Some researchers believe that it could affect
neurodegeneration via the inhibition of tau protein aggregation and amyloid
formation.
Methylene blue is available online or through prescription
form your HEAOPS practitioner who understands how and when to use it. It is
available both in an oral form as well as intravenously. Adding red light
therapy enhances the effects of methylene blue.
Typical does is between 02. Mg/kg to 2mg/kg.
Some precautions must be considered, and it is best to
consult with your practitioner before use.
LINKS
The Ultimate Guide to Methylene Blue by Mark Sloan: https://amzn.to/3f7vl3X
Interview with Mark Sloan author of The Ultimate Guide to Methylene
Blue:
Methylene
Blue: A safe, effective, and affordable biohack – Limitless Mindset
Methylene
Blue – A safe, effective, and affordable biohack [Mark Sloan Interview]
(rumble.com)
Methylene Blue tincture for upgrading cognitive health: https://amzn.to/3R7BPxc
Scientific Literature:
Multimodal Randomized Functional MR Imaging of the Effects
of Methylene Blue in the Human Brain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084971/
Methylene
blue reduces aβ levels and rescues early cognitive deficit by increasing
proteasome activity: https://pubmed.ncbi.nlm.nih.gov/20731659/
Disclaimers
If you want to live longer and have a higher quality of
life: recognize that there are many health optimizing strategies available to
you but first the appropriate diagnostics are necessary to determine best
strategies for you.
Find a practitioner that understands how to tap into
optimizing your health with the many types of modalities not taught in medical
school. There is a very important role
to have your doctors and hospitals help you in an emergency but it is on you to
make sure you optimize your health. That is my mission: to curate and guide any
consumer of health with the many incredible products, devices and services that
will optimize you.
Each of these recommendations is evidence based and diligent
research will find the appropriate documentation. Before instituting any type
of health optimization, obtain the consultation from your medical practitioner.
All information on this platform is not to be considered as medical advice and
therefore the authors assume no liability for any actions taken by any
individual.
If you are a practitioner or a consumer looking for a
practitioner, follow the link below for additional references that can guide
you towards optimizing your mitochondria and potentially reversing any medical
condition.
As medical practitioners we have an incredible opportunity
to enhance our influence on those that trust us the most, our clients as
patients. This requires embracing strategies not commonly taught in medical
school and partnering with the types of health practitioners that can support
the many different health optimization strategies that are available. My
personal mission is to support all types of health practitioners to re-invent
their practice and find new pathways to help their business thrive and deliver
better results in community health as we can curate and guide or clients with
the best options now available to them. For more information, contact me
through the website.
Bart Rademaker, MD
